New SOS Reference Library: Dearomatizations
The new Science of Synthesis reference library Dearomatizations was edited by David Sarlad (Rice University, Texas, USA). It presents dearomatization as a foundational strategy for converting simple aromatic compounds into complex 3D molecular frameworks, reflecting a field that has expanded dramatically over the last two decades.
Prof. David Sarlah, from Rice University in Texas (USA) is the editor of the SOS reference library Dearomatizations.
Dearomatization is a fundamental chemical transformation of arenes, involving some of the most efficient methods for rapid and selective generation of complexity from simple aromatic compounds. While the toolbox of dearomatization was once limited to a handful of reactions, dearomative chemistry has expanded significantly over the past two decades. Today, more sophisticated methods enable for the incorporation of diverse functionalities under milder conditions.
This new Science of Synthesis volume is an essential reference, covering all aspects of dearomative chemistry, from classic transformations such as the Birch reduction to cutting-edge developments in asymmetric catalysis, photochemistry, and electrochemistry. In addition to providing a broad overview of the landscape, particular emphasis is placed on practical methods that provide enhanced control over chemo-, regio-, and stereoselectivity.