The SOS Online Library Comprises More than 300 Volumes
The Science of Synthesis eBook collection comprises more than 300 volumes, covering over a century of synthetic organic chemistry. Original German print editions of Houben-Weyl have been digitized, and new digital issues of English language Science of Synthesis (SOS) have been added to the online library, covering some of the most current topics in organic and organometallic chemistry, such as click chemistry and organofluorine chemistry.
Houben-Weyl
Houben-Weyl – Methoden der Organischen Chemie (Methods of Organic Chemistry) is a standard reference work covering preparative methods for chemists engaged in organic synthesis. The first volume “Analytic Methods” was published in 1908. The Houben-Weyl Collection contains 161 volumes.
Original Edition
The “Science of Synthesis Original Edition” is a comprehensive reference work that offers a critical review of synthetic methods in organic and organometallic chemistry. The series comprises 48 titles which were published between 2000 and 2010. The Original Edition was compiled by the collaborative efforts of chemists from both industry and academia.
Knowledge Updates
In order to enable chemists to keep up with the latest trends in organic synthesis, Science of Synthesis has been continuously extended with fresh content since 2010. Chapters of the Original Edition are updated with high quality content and new methods and new product (sub)classes are added.
Reference Library
The volumes of the Reference Library add topics of particular current interest to Science of Synthesis. The supplementary series highlights new angles and perspectives of importance in organic synthesis. It focuses on specialized topics in organic synthesis, offering expert-reviewed methods, practical guidance, and in-depth coverage of emerging areas in chemistry.
Content Updates
Science of Synthesis (SOS Platform) is regularly updated. After registering for the e-mail newsletter, you will receive an e-mail alert whenever new content is added.
Latest News from the SOS Editorial Office
Case Study: Unsymmetrical Polysulfidation
Our research group has long been committed to sulfur chemistry. In particular, polysulfide synthesis attracts our attention due to the potential medicinal and material properties of polysulfides. Thus, we designed and synthesized bilateral disulfurating reagents to investigate better methodologies for polysulfide synthesis (Scheme 1).
New SOS: Exclusive Sneak Preview
Science of Synthesis is moving on to a new chapter and we are excited to share a preview of what’s coming. Discover how the new, more intuitive platform will make daily work smoother, faster, and more efficient for anyone involved in organic synthesis.
Recommended by Leading Chemists
Science of Synthesis Is Recommended by Leading Chemists: Top chemists worldwide highlight SOS for its exceptionally well-organized insights into organic chemistry, which are tailored for graduate students, as well as scientists and researchers in academia and industry.
Release 4.32
We are thrilled to announce that Professor David Sarlah from Rice University, USA, becomes a member of the Science of Synthesis Editorial Board with effect of October 1st, 2025. David obtained his bachelor’s degree in chemistry from the University of Ljubljana in his home country Slovenia before moving to the…
David Sarlah
We are thrilled to announce that Professor David Sarlah from Rice University, USA, becomes a member of the Science of Synthesis Editorial Board with effect of October 1st, 2025. David obtained his bachelor’s degree in chemistry from the University of Ljubljana in his home country Slovenia before moving to…
Tehshik Yoon
We are excited to report that Professor Tehshik P. Yoon from the University of Wisconsin-Madison, USA, joins the Science of Synthesis Editorial Board as a new member with effect of October 1st, 2025. Tehshik was born in Montréal (Canada) and grew up in Blacksburg, VA (USA). He earned his AB…
SOS Knowledge Updates: Volume Editor Renzo Luisi
Renzo Luisi, of the University of Bari (Italy), has joined the team of editors for the SOS Knowledge Updates series. He will be responsible for content relating to Volume 8 on Compounds of Group 1 (Li...Cs).