The SOS Online Library Comprises More than 300 Volumes
The Science of Synthesis eBook collection comprises more than 300 volumes, covering over a century of synthetic organic chemistry. Original German print editions of Houben-Weyl have been digitized, and new digital issues of English language Science of Synthesis (SOS) have been added to the online library, covering some of the most current topics in organic and organometallic chemistry, such as click chemistry and organofluorine chemistry.
Houben-Weyl
Houben-Weyl – Methoden der Organischen Chemie (Methods of Organic Chemistry) is a standard reference work covering preparative methods for chemists engaged in organic synthesis. The first volume “Analytic Methods” was published in 1909. The Houben-Weyl Collection contains 161 volumes.
Original Edition
The “Science of Synthesis Original Edition” is a comprehensive reference work that offers a critical review of synthetic methods in organic and organometallic chemistry. The series comprises 48 titles which were published between 2000 and 2010. The Original Edition was compiled by the collaborative efforts of chemists from both industry and academia.
Knowledge Updates
In order to enable chemists to keep up with the latest developments in organic synthesis, Science of Synthesis has been continuously extended with fresh content since 2010. Chapters of the Original Edition are updated with high quality content and new methods and new product (sub)classes are added.
Reference Library
The volumes of the Reference Library add topics of particular current interest to Science of Synthesis. The supplementary series highlights new angles and perspectives of importance in organic synthesis. It focuses on specialized topics in organic synthesis, offering expert-reviewed methods, practical guidance, and in-depth coverage of emerging areas in chemistry.
Content Updates
Science of Synthesis (SOS Platform) is regularly updated. After registering for the e-mail newsletter, you will receive an e-mail alert whenever new content is added.
Latest News from the SOS Editorial Office
Thieme Cheminars: Presented by SOS
Thieme Cheminars is a series of free-to-attend online seminars that cover topics at the forefront of chemical research. These mini-symposia are presented by Science of Synthesis and Thieme's chemistry journals.
Case Study: Synthetic Strategies toward Lactones
Take a look at this SOS case study by Yingmin Ji and Dr. Albert Granados at the Universitat Autònoma de Barcelona in Spain. It focuses on the synthesis of lactones and explains how to use SOS as a structure-based planning tool.
Thieme Has Signed National Agreement for SOS
Stuttgart: Thieme has signed a German agreement with FID Chemie – Fachinformationsdienst Chemie to provide nationwide access to Science of Synthesis, our flagship synthetic chemistry reference database.
New SOS Reference Library: Dearomatizations
The new Science of Synthesis volume "Dearomatizations", edited by David Sarlah, serves as an essential reference, covering all aspects of dearomative chemistry, from classic transformations such as the Birch reduction to cutting-edge developments in asymmetric catalysis, photochemistry, and electrochemistry.
Case Study: Discovering an Improved Synthetic Route to [1.1.1]Propellane
Check out this case study, focusing on the topic of ring-strain chemistry, from Kasmita Singha at the Indian Institute of Science (IISc) in Bangalore, and learn more about how SOS can help you in your day-to-day work.
Mariola Tortosa Becomes New SOS Board Member
We are delighted to welcome Professor Mariola Tortosa from Universidad Autónoma de Madrid (Spain) as a new member of the Science of Synthesis Editorial Board. Her research interests include boron chemistry, asymmetric catalysis and the synthesis of natural products.
New SOS: Now Online on Thieme Serve
Science of Synthesis is now available on a new platform. The new SOS makes your daily work faster and more efficient—while offering the same trusted, expert‑curated content.
Explore Modern Strategies in Organofluorine Chemistry
Jean-François Paquin is the Volume Editor of the SOS Reference Library series “Modern Strategies in Organofluorine Chemistry”. In this news, he shares an inspiring perspective on how electrochemistry is driving innovation in organofluorine chemistry.
Case Study: Enantioselective Hydroselenation of Unsaturated Hydrocarbons
Check out this case study from Chen Cui, working on organoselenium chemistry at the Beijing Institute of Technology (PR China) and learn more about how SOS can help you in your day-to-day work.
New SOS: Exclusive Sneak Preview
Science of Synthesis is moving on to a new chapter and we are excited to share a preview of what’s coming. Discover how the new, more intuitive platform will make daily work smoother, faster, and more efficient for anyone involved in organic synthesis.